A Closed-Loop Optogenetic Stimulation Device
نویسندگان
چکیده
منابع مشابه
Closed-Loop and Activity-Guided Optogenetic Control
Advances in optical manipulation and observation of neural activity have set the stage for widespread implementation of closed-loop and activity-guided optical control of neural circuit dynamics. Closing the loop optogenetically (i.e., basing optogenetic stimulation on simultaneously observed dynamics in a principled way) is a powerful strategy for causal investigation of neural circuitry. In p...
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Dynamic oscillatory coherence is believed to play a central role in flexible communication between brain circuits. To test this communication-through-coherence hypothesis, experimental protocols that allow a reliable control of phase-relations between neuronal populations are needed. In this modeling study, we explore the potential of closed-loop optogenetic stimulation for the control of funct...
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OBJECTIVE Controlling neural activity enables the possibility of manipulating sensory perception, cognitive processes, and body movement, in addition to providing a powerful framework for functionally disentangling the neural circuits that underlie these complex phenomena. Over the last decade, optogenetic stimulation has become an increasingly important and powerful tool for understanding neur...
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Implantable neurostimulators have rapidly become established methods of treating a variety of neurological disorders. The development of implantable neural interfaces enable the testing of Norbert Wiener’s hypotheses regarding neural disorders and their relationship to ideas of cybernetics. However, currently deployed medical devices of this kind are open-loop. For example, DBS for treatment of...
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We integrate electrothermally induced micro-pumps and dielectrophoretic (DEP) traps into micro-circulating fluidic channel loops for yeast cell concentration and separation, two important on-chip cell manipulation tasks, with the same embedded electrodes on-chip. Each fluidic loop design contains well-defined high and low field regions that serve for both fluid transport and cellular manipulati...
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ژورنال
عنوان ژورنال: Electronics
سال: 2020
ISSN: 2079-9292
DOI: 10.3390/electronics9010096